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August
APS E-News
Your
Ideas Needed for National Pain Awareness
Month
September
is National Pain Awareness month, and
APS is helping members promote Pain Awareness
by sharing ideas with this survey.
Please
participate by telling us how you and
your organization help promote pain awareness,
research and treatment to the general
public, or to other audiences (legislative,
eductional institutions, the medical community,
etc.). All responses are anonymous; we
will just summarize results and report
to the APS membership. Please click
here to complete this brief 4 question
survey.
And
to celebrate National Pain Awareness month,
you will recieve a bonus issue of APS
E-News in September, which will highlight
pain awareness activities and themes.
Legislative
Update: National Pain Care Policy Act
Introduced in Senate
APS
is please to report the introduction of
a new Senate companion to the House's
National Pain Care Policy Act of 2007
(HR 2994), which calls for improved pain
care, research, education, access, and
funding. The Senate's National Pain Care
Policy Act of 2008, S3387, was introduced
by Senators Dodd (D-CT) and Hatch (R-UT).
According
to APS legislative counsel Bob Saner,
the Senate bill is a "true companion"
to HR 2994. He notes only slight technical
differences in the bills. "The key
now is to [first] move it forward in the
House and make sure the Senate is receptive,"
he says. Saner is awaiting more information
on S. 3387 before enlisting the help of
APS members in recruiting cosponsors.
At APS E-News deadline, the House bill
had more than 50 cosponsors.
Right
before the August recess, the House unanimously
passed HR 6445, the Veterans Health Care
Policy Enhancements Act of 2008. Efforts
on the part of APS will now turn toward
getting that legislation passed into law
in September. This will entail helping
to get the Senate bill passed in the House,
the House bill passed in the Senate, or
a larger comprehensive bill passed in
both chambers—the most likely alternative.
The
Mayday Fund Announces 2008-2009 Mayday
Fellows
The
Mayday Fund announced the selection of
six experts in pain management to be fellows
under The Mayday Pain and Society Fellowship.
The new fellows hail from across the United
States and Canada, specializing in a wide
range of healthcare disciplines including
anesthesiology, nursing, pharmacy pediatrics,
and pain policy.
APS
extends special congratulations to the
six new fellows-Paul Christo, Lisa Robin,
Bonnie Stevens, Scott Strassels, Anna
Taddio, and William Zempsky-all of whom
are APS members.
"The
caliber of candidates for this fellowship
continues to amaze us, and we wish we
could have awarded a fellowship to so
many more," said Russell Portenoy,
MD, Mayday Fellowship Advisory Committee
Chair, and chair of the Department of
Pain Medicine and Palliative Care at Beth
Israel Medical Center. "The twenty-four
fellows who have been through the program
to date are true leaders in pain management,"
he said. "They bring new energy and
focus to pain issues that need so much
attention. We know the six new fellows
will expand the effort."
2008-2009
Fellows
Paul Christo, MD MBA
The Johns Hopkins University School of
Medicine
Lisa Robin, Senior Vice President
Federation of State Medical Boards
Bonnie Stevens, MSN PhD
University of Toronto Hospital for Sick
Children
Scott Strassels, PharmD PhD BCPS
University of Texas at Austin Division
of Pharmacy
Anna Taddio, PhD
University of Toronto Hospital for Sick
Children
William Zempsky, MD,
Connecticut Children's Medical Center
and the University of Connecticut School
of Medicine.
Established
in 2003, the Fellowship provides leaders
in the pain management field with tools
and skills to advocate on behalf of better
treatment for pain. Thirty fellows will
have completed the program by 2009. Applications
will be accepted for the sixth year of
the Mayday Fellowship in early 2009. Six
more applicants will be chosen. For more
information, visit www.maydayfellows.org.
The
Journal of Pain Highlights
The following highlights summarize selected
articles from the August 2008 (volume
9, number 8).
Massage
Reduces Pain Perception and Hyperalgesia
in Experimental Muscle Pain: A Randomized,
Controlled Trial
Laura A. Frey Law, Stephanie Evans, Jill
Knudtson, Steven Nus, Kerri Scholl, Kathleen
A. Sluka; Program in Physical Therapy
and Rehabilitation Science, The University
of Iowa, Iowa City, Iowa.
For
those who experience lingering pain following
exercise, a relaxing deep massage can
help relieve musculoskeletal pain associated
with exercise-induced pain, according
to research reported in The Journal
of Pain.
Researchers
at the University of Iowa performed a
double-blinded, randomized controlled
trial to study the effects of massage
on pressure-pain thresholds and perceived
pain using delayed muscle soreness following
exercise as the pain measurement. Trial
participants were divided into three groups:
no-treatment (control), superficial touch,
and deep tissue massage. Pain was assessed
before treatment, after exercise, and
before and after treatment.
Massage
has been used for rehabilitation and relaxation
for thousands of years with no adverse
effects. Unfortunately, few well-controlled
trials of massage exist either in clinical
or experimentally induced pain populations.
The purpose for the study, therefore,
was to determine the effects of massage
using an endogenous muscle-pain model
on otherwise healthy individuals.
The
authors found that subjects given deep-tissue
massage were able to increase their pain
thresholds and decrease stretch pain compared
with the no-treatment group. When combining
the deep-tissue massage and light-touch
groups, they found that stretch-pain reductions
remained significantly better than in
the control group although the light-touch
treatment was not significantly better
than no treatment.
The
authors concluded that their study demonstrates
that soft-tissue massage can reduce hyperalgesia
and pain using a delayed onset muscle
soreness model. The findings support use
of massage to reduce stretch-pain perception
and hyperalgesia.
A
Pilot Study of Potassium Supplementation
in the Treatment of Hypokalemic Patients
with Rheumatoid Arthritis: A Randomized,
Double-Blinded, Placebo-Controlled Trial
Reza Rastamanesh,1 Amin S.
Abargouel,1 Zhaleh H. Shadman,1
Ali A. Ebgrahimi,2 and Charles
E. Weber3
(1) Faculty of Nutrition and
Food Sciences, Department of Human Nutrition,
Shaheed Beheshti University of Medical
Sciences (SBMU), Tehran, Iran
(2) Sina Teaching Hospital,
Tabriz Medical Sciences University, Tabriz,
Iran
(3) Hendersonville, North Carolina.
In
the first study of its kind, published
in The Journal of Pain, a team
of Iranian researchers showed that oral
potassium supplementation can decrease
pain intensity in rheumatoid arthritis
(RA) patients.
Researchers
examined patients given orally administered
white grape juice with 6,000 mg of potassium
per day, compared with those given placebo
grape juice. Thirty-six female subjects
diagnosed with RA enrolled in the study.
In the potassium group, 43% had 33% lower
pain intensity and 31% showed moderate
pain intensity reduction compared to the
control group.
The
authors concluded that the pilot study
associated high potassium intake with
an improvement in RA symptoms and lower
disease activity and pain intensity. They
noted their findings could be relevant
for planning dietary regimens for RA patients.
Pain
Medicine Highlights
The following highlights summarize selected
articles from the
June 2008 issue (volume 9, number 4).
Sleep-Disordered
Breathing and Chronic Opioid Therapy
Lynn R. Webster, MD,1 Youngmi
Choi, MD PhD,2 Himanshu Desai,
MD, 2,3 Linda Webster, RPSGT,4
and Brydon J.B. Grant, MD.2,3,5
(1)
Lifetree Clinical Research and Pain Clinic,
Salt Lake City, UT.
(2) Department of Medicine,
Physiology and Biophysics, Social and
Preventative Medicine and Biostatistics,
University at Buffalo SUNY, Buffalo, NY.
(3) Departments of Physiology
and Biophysics, Social and Preventative
Medicine and Biostatistics, University
at Buffalo SUNY, Buffalo, NY.
(4) Medical One Medical, Sandy,
UT.
(5) Veteran Affairs Healthcare
System, Buffalo, NY.
Recent increases in deaths believed to
be associated with unintentional overdoses
of the drug, methadone, provide the background
for an observational study of patients
with chronic pain and sleep apnea. An
apnea-hypopnea index measured the intensity
of sleep apnea and assessed the relationship
between chronic pain and sleep apnea medications
in 140 patients.
Opioids
are commonly prescribed for patients with
chronic pain, but they are also associated
with a risk for sleep apnea. The study
examined whether methadone might cause
sleep disorder problems overnight that
could affect a patient's mortality.
Data
was analyzed for 140 patients who had
opioids for chronic pain around-the-clock.
Demographics were collected for age, gender,
race, body mass index, disease history,
family history, and primary diagnosis,
in addition to pain-related information.
Data on patients studied while sleeping
were collected and rated on three indices.
The apnea-hypopnea index measured how
many apneas (absence of air flow for at
least 10 seconds) the patient had in an
hour of sleep. The central sleep apneas
index measured how many central sleep
apneas occurred per hour of sleep. Additionally,
the number of obstructive and mixed apneas
per hour were examined with the obstructive/mixed
apnea index.
All
patients in the study took opioid medications;
however, not all patients took methadone.
Abnormal apnea-hypopnea index scores were
submitted for 75% of the patients in the
study. The results showed that obstructive
and central sleep apnea was significantly
more common in the study than in the general
population. Although a connection was
drawn between those taking methadone and
having sleep apneas, no connection was
made with other opioids. The authors concluded
that sleep apneas were more common with
methadone and also benzodiazepines so
caretakers must use additional caution
when monitoring patients taking opioids.
What Percentage of Chronic Nonmalignant
Pain Patients Exposed to Chronic Opioid
Analgesic Therapy Develop Abuse/Addiction
and/or Aberrant Drug-Related Behaviors?
A Structured Evidence-Based Review
David A. Fishbain, MD,1,2,3,4,5,6
Brandly Cole, PsyD,6,7 John
Lewis, PhD,1,2 Hubert L. Rosomoff,
MD DMedSc FAAPM,1,2,3,4,6,7
and R. Steele Rosomoff, BSN MBA1,2,3,4,6,7
(1)
Miller School of Medicine at the University
of Miami, Miami, FL
(2) Department of Neurological
Surgery, University of Miami, Miami, FL
(3) Department of Psychiatry
and Anesthesiology, University of Miami,
Miami, FL
(4) Department of Anesthesiology,
University of Miami, Miami, FL
(5) Department of Psychiatry,
Miami VA Medical Center, Miami, FL
(6) The Rosomoff Comprehensive
Pain Center, Douglas Gardens, Miami, FL
(7) Douglas Gardens, Miami,
FL
Researchers interested in knowing what
percentage of chronic malignant pain patients
exposed to chronic opioid analgesic therapy
will develop an addiction or abuse the
medicine examined 67 existing studies
in detail.
For
years, the stance on whether or not opioid
therapy caused addiction varied. In a
review of nine studies, Portenoy determined
that addiction occurred as a result of
the drug properties themselves, and the
psychological mindset the patient brought
into treatment, although these patient
variables were generally uncommon. Other
reviews, such as one by Aronoff, note
that it is not regular opioid use that
causes addiction but the inappropriate
usage of opioids. This risk is higher
in those who already have a high risk
for substance abuse problems. A third
review by Bartleson suggested that chronic
opioid analgesic therapy was associated
with a low risk of abuse or addiction.
The
detailed study of 67 existing reviews
was executed by searching MEDLINE, Psychological
Abstracts, Science Citation Index, and
the National Library of Medicine Physician
Data Query, using key terms related to
opioid abuse. Each study was rated to
describe how relevant it was to the study.
The
overall incidence of opioid abuse or addiction
was 3.27%. Some studies stated that this
percentage would be lower if recognized
problematic criteria were used earlier.
Findings indicated that a tendency toward
addiction was genetically based, so knowing
the family history would be helpful for
physicians.
Future
studies should document opioid exposure
times and document opioid doses at which
addiction or abherrant drug-related behaviors
are observed. Use of chronic opioid analgesic
therapy will likely only lead to abuse
or addiction behaviors in a very small
percentage of users, and can be lessened
further by examining their history.
APS
Volunteer Spotlight: Robert Jamison, PhD
For those concerned about the future of
pain research, Bob Jamison, PhD,
a longtime APS volunteer and annual meeting
contributor, says, "There still are
some Nobel Prizes to be won." He
is passionate about the potential for
pain research to bring long-awaited breakthroughs
for millions who suffer chronic pain.
A
psychologist, Jamison began his career
in the pain care field in 1983 while at
Vanderbilt Medical School. He also joined
APS at that time as a way to "get
immersed in the field." He knew APS
would offer opportunities to meet new
colleagues, build relationships with top
thought leaders, and find opportunities
for research collaborations.
"I
was inspired by the work of Dennis Turk
and Frank Keefe and decided to focus my
interests in the area of behavioral medicine
and pain," Jamison told APS E-News.
"I enjoyed meeting the members at
APS conferences and received excellent
support for my own studies."
Positive
feedback encouraged Jamison to get involved
as an APS volunteer and he hasn't stopped
since. "What I liked about the APS
conferences was the unique opportunities
they presented for multidisciplinary information
exchanges and collaborations. They were
not overwhelming and I always came home
with new ideas."
Jamison
has been on numerous APS committees and
SIGs and also served on the APS Board
of Directors and Executive Committee.
He will be the chair of the 2010 APS Annual
Meeting Scientific Program Committee.
"The meeting format isn't broken,
so there's no need to fix it," he
said. "Of course, we'll look to make
some improvements and continue to offer
a strong balance between science and clinical
practice."
Jamison
noted that translational research has
become a major priority within APS and
believes this focus can foster more extensive
multidisciplinary research collaborations
in the pain field.
Although
he is actively involved in research, Jamison
sees pain patients every day at the Pain
Management Center of Brigham and Women's
Hospital in Boston. "We have a lot
to learn in this field, especially in
knowing more about how pain influences
mood and sleep and the long-term implications
for chronic pain patients.
Jamison
has published extensively on how can clinicians
can better track and apply patient feedback
about their pain experiences. He recently
coauthored a study in The Journal of Pain
in which the team evaluated a new screening
tool to predict which pain patients are
most likely to exhibit aberrant medication-related
behavior.
Call
for Nominations for the APS Board of Directors
Nominating
and electing the leadership of APS is
an important and fundamental responsibility
of all society members. But what are the
benefits to the volunteer of stepping
up for a leadership role, whether as director,
nominating committee member, or other
officer? Volunteer leaders have an unparalleled
opportunity to work at the strategic level
to affect the direction of the association.
Perhaps strategic planning has not been
a significant part of your daily routine.
Election to a board of directors' position
provides the opportunity and challenge
to develop these perhaps unfamiliar skills.
A leadership position also affords the
opportunity to represent the needs of
the membership, and to advance the profession
or the industry.
Are
you looking for a new challenge or opportunity
for growth? Perhaps you know a colleague
who is motivated, dedicated, and inspired
about the future of APS or advancing the
knowledge and treatment of pain. Please
start thinking now about who you might
nominate for the APS Board of Directors
or Nominating Committee.
The
call for nominations will be sent to all
APS members in October to nominate potential
election candidates. Position descriptions,
current list of board and Nominations
Committee members, vacancies and the disciplinary
composition and geographic representation
of the board will be available in the
members-only section of the APS website.
Nominees must be regular APS members.
Please
watch for notification of the nominations
process and be prepared to take advantage
of this opportunity. Your participation
is important to APS.
PPSG
Release 2008 Policy Evaluation Reports
The
University of Wisconsin Pain & Policy
Studies Group (PPSG) recently announced
the release of two new resources, which
are part of the PPSG's continuing pain
and public policy research program.
The
Evaluation Guide is the fifth in a series
of evaluations of federal and state pain
policies. The Progress Report Card quantifies
state pain policies and tracks progress
to promote pain management and reduce
policy barriers by comparing 2008 state
policy grades with those from 2000, 2003,
2006, and 2007. These two reports are
important tools that can be used by government
and nongovernment organizations, as well
as policy-makers, healthcare professionals,
and advocates to understand the policies
in their state that reinforce the right
to pain management, or that can hinder
patient access to effective treatment.
Visit
the PPSG Web site at www.painpolicy.wisc.edu.
Call
for Paper and Poster Abstracts
The
Call for Paper and Poster Abstracts will
be available on the APS Web site beginning
September 1. Please watch future issues
of APS E-News for updates.
Pain
in the News
Georgia
Shows Greatest Improvement in Patient
Pain Policies
Click
here
to read more pain-related news in the
media.
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